Trade Summary

1 week ago, Orbimed Advisors LLC, serving as Dir at Sionna Therapeutics, Inc. (SION), sold 33,356 shares at $44.55 per share, for a total transaction value of $1,486,010.00. Following this transaction, Orbimed Advisors LLC now holds 3,561,655 shares of SION.

This sale represents a 1.00% decrease in Orbimed Advisors LLC's stake in the company. This is considered a medium-conviction trade.

The trade was executed on Wednesday, December 24, 2025 and publicly disclosed via SEC Form 4 filing on Monday, December 29, 2025, 5 days after the trade was made.

Sionna Therapeutics, Inc. operates in the HEALTHCARE sector, specifically within the BIOTECHNOLOGY industry. Insider selling activity in this sector can provide valuable signals about industry trends and company-specific developments.