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SLGL - Sol-Gel Technologies Ltd.

Insider Purchase by Opaleye Management Inc. (10%)

3 Months
After Trade
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Trade Summary

1 month ago, Opaleye Management Inc., serving as 10% owner at Sol-Gel Technologies Ltd. (SLGL), purchased 66,304 shares at $41.97 per share, for a total transaction value of $2,782,904.00. Following this transaction, Opaleye Management Inc. now holds 453,739 shares of SLGL.

This purchase represents a 17.00% increase in Opaleye Management Inc.'s stake in the company. This is considered a high-conviction trade given the significant change in ownership.

The trade was executed on Monday, December 29, 2025 and publicly disclosed via SEC Form 4 filing on Wednesday, December 31, 2025, 2 days after the trade was made.

Sol-Gel Technologies Ltd. operates in the HEALTHCARE sector, specifically within the BIOTECHNOLOGY industry. Insider buying activity in this sector can provide valuable signals about industry trends and company-specific developments.

Opaleye Management Inc.

Opaleye Management Inc.

10%

Opaleye Management Inc. is a hedge fund management firm based in Boston, Massachusetts, founded in February 1996 by James Aaron Silverman, who serves as President and Chief Compliance Officer.[[1]](https://www.insidermonkey.com/hedge-fund/opaleye+management/647/) Originally named Risk/Reward Capital Management Corporation, it rebranded to Opaleye Management in 2014 and specializes in investing in small and mid-sized biotechnology and specialty pharmaceutical companies in the US and internationally.[[1]](https://www.insidermonkey.com/hedge-fund/opaleye+management/647/) The firm manages approximately $639 million in discretionary assets for two clients, with recent 13F filings showing a portfolio value of around $494 million, including top holdings like Ocular Therapeutix Inc. and Harrow Inc.[[1]](https://www.insidermonkey.com/hedge-fund/opaleye+management/647/)[[6]](https://whalewisdom.com/filer/opaleye-management-inc) Opaleye Management Inc. is frequently classified as a 10% owner in various portfolio companies due to its significant stakes, such as in Eton Pharmaceuticals Inc., Protara Therapeutics Inc., and recently Sol-Gel Technologies Ltd. (SLGL), where it purchased 66,304 shares to increase its position.[[2]](https://www.gurufocus.com/insider/52142/opaleye-management-inc.)[[10]](https://www.tipranks.com/news/insider-trading/major-stakeholder-makes-bold-new-move-in-sol-gel-technologies-insider-trading) As of late 2025, its estimated net worth from insider holdings exceeds $378 million across multiple biotech firms.[[2]](https://www.gurufocus.com/insider/52142/opaleye-management-inc.) The firm continues active trading, including recent purchases in SANUWAVE Health, Inc.[[3]](https://www.investing.com/news/insider-trading-news/opaleye-management-buys-sanuwaves-health-shares-worth-38360-93CH-4280776)

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Trade Price

$41.97

Quantity

66,304

Total Value

$2,782,904.00

Shares Owned

453,739

Trade Date

Monday, December 29, 2025

55 days ago

SEC Filing Date

Wednesday, December 31, 2025

Filed 2 days after trade

HEALTHCAREBIOTECHNOLOGY

About Sol-Gel Technologies Ltd.

Company Overview

No company information available
View news mentioning SLGL

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