Dir
EcoR1 Capital, LLC is a San Francisco-based biotech-focused investment firm founded in 2012 or 2013 by Oleg Nodelman, who serves as its Founder and Portfolio Manager.[[1]](https://www.ecor1cap.com/team-members/oleg-nodelman)[[2]](https://www.insidermonkey.com/hedge-fund/ecor1+capital/832/)[[3]](https://www.ecor1cap.com/about) The firm specializes in investing across all stages of research and development in the biotechnology sector, particularly in healthcare, life sciences, and oncology, with a patient-driven ethos that emphasizes exceptional management, strong science, and innovative therapeutics.[[1]](https://www.ecor1cap.com/team-members/oleg-nodelman)[[2]](https://www.insidermonkey.com/hedge-fund/ecor1+capital/832/)[[3]](https://www.ecor1cap.com/about) It manages discretionary assets of approximately $5 billion as reported in early 2024, with a portfolio value around $2-4 billion in recent filings, featuring top holdings such as Zymeworks Inc., AnaptysBio, Inc., and Apellis Pharmaceuticals.[[2]](https://www.insidermonkey.com/hedge-fund/ecor1+capital/832/)[[6]](https://fintel.io/i/ecor1-capital-llc)[[7]](https://whalewisdom.com/filer/ecor1-capital-llc)
EcoR1 Capital, LLC operates from 357 Tehama Street, Floor 3, San Francisco, CA, and has established itself as a significant player in biotech investing, holding board positions or significant ownership in companies like Zymeworks (as Director and 10% Owner), AnaptysBio, and Galapagos through its leadership.[[1]](https://www.ecor1cap.com/team-members/oleg-nodelman)[[5]](https://www.gurufocus.com/insider/43801/ecor1-capital,-llc) The firm recently traded as a Director at Aktis Oncology, Inc. (AKTS), reflecting its active involvement in oncology-related investments.[user query context] With over 30 holdings and a concentrated top-10 portfolio allocation, EcoR1 supports advancements in treatments for cancer, immunology, and autoimmune diseases.[[6]](https://fintel.io/i/ecor1-capital-llc)[[7]](https://whalewisdom.com/filer/ecor1-capital-llc)
View full insider profile →