AMLX - Amylyx Pharmaceuticals, Inc.

Insider Sale by Frates James M (CFO)

1 Month
After Trade
Before Trade

Loading data...

Trade Summary

3 days ago, Frates James M, serving as CFO at Amylyx Pharmaceuticals, Inc. (AMLX), sold 7,909 shares at $14.52 per share, for a total transaction value of $114,851.00. Following this transaction, Frates James M now holds 292,169 shares of AMLX.

This sale represents a 3.00% decrease in Frates James M's stake in the company. This is considered a medium-conviction trade.

The trade was executed on Monday, March 2, 2026 and publicly disclosed via SEC Form 4 filing on Wednesday, March 4, 2026, 2 days after the trade was made.

Amylyx Pharmaceuticals, Inc. operates in the HEALTHCARE sector, specifically within the BIOTECHNOLOGY industry. Insider selling activity in this sector can provide valuable signals about industry trends and company-specific developments.

Frates James M

CFO

James M. Frates is the Chief Financial Officer (CFO) of Amylyx Pharmaceuticals, Inc. (AMLX), a clinical-stage biopharmaceutical company focused on developing treatments for amyotrophic lateral sclerosis (ALS), Alzheimer’s disease, and other neurodegenerative diseases. He joined Amylyx effective January 25, 2021, bringing extensive experience from his prior role as CFO at Alkermes plc from 1998 to 2021, where he helped grow the company from a clinical-stage entity to an international operation with over $1 billion in revenue, 2,000 employees, and multiple products through acquisitions and financings.[[1]](https://www.amylyx.com/news/james-frates-joins-amylyx-pharmaceuticals-as-chief-financial-officer)[[2]](https://theorg.com/org/amylyx/org-chart/james-m-frates)[[3]](https://www.marketscreener.com/insider/JIM-FRATES-A02MI9/) Frates has recently engaged in insider trading at AMLX and holds approximately 291,502 to 317,519 shares valued at around $2-4 million as of 2025-2026.[[3]](https://www.marketscreener.com/insider/JIM-FRATES-A02MI9/)[[5]](https://www.gurufocus.com/insider/30638/james-m-frates) Prior to Alkermes, Frates served as Vice President in Biotechnology Investment Banking at Robertson Stephens & Company (1992-1998) and worked at Morgan Stanley.[[1]](https://www.amylyx.com/news/james-frates-joins-amylyx-pharmaceuticals-as-chief-financial-officer)[[2]](https://theorg.com/org/amylyx/org-chart/james-m-frates) He currently serves as an Independent Director at Sage Therapeutics, Inc. since 2014, and as a trustee for St. Francis House and Roxbury Latin School.[[1]](https://www.amylyx.com/news/james-frates-joins-amylyx-pharmaceuticals-as-chief-financial-officer)[[3]](https://www.marketscreener.com/insider/JIM-FRATES-A02MI9/) Frates holds a Bachelor's degree in Political Science and Government from Harvard College and an MBA from Harvard Business School.[[1]](https://www.amylyx.com/news/james-frates-joins-amylyx-pharmaceuticals-as-chief-financial-officer)[[2]](https://theorg.com/org/amylyx/org-chart/james-m-frates)[[4]](https://www.bizjournals.com/boston/news/2022/07/15/als-biotech-amylyx-pharmaceuticals-has-grown-with.html) His personal connection to ALS, through his cousin Pete Frates' diagnosis and the Ice Bucket Challenge, motivates his commitment to Amylyx's mission.[[1]](https://www.amylyx.com/news/james-frates-joins-amylyx-pharmaceuticals-as-chief-financial-officer)

View full insider profile →

Trade Price

$14.52

Quantity

7,909

Total Value

$114,851.00

Shares Owned

292,169

Trade Date

Monday, March 2, 2026

3 days ago

SEC Filing Date

Wednesday, March 4, 2026

Filed 2 days after trade

HEALTHCAREBIOTECHNOLOGY

About Amylyx Pharmaceuticals, Inc.

Company Overview

No company information available
View news mentioning AMLX

💬 Want Deeper Insight?

Use our AI assistant to ask questions about this trade, the insider, or the company.

Chat with AI

Share this trade

https://insidersignal.ai/trade/4496386

🚀 Track Insider Trades in Real-Time

Create a free account to access our full database of insider trades, AI-powered analysis, price alerts, and discover what corporate executives are buying and selling.

✓ Free forever plan available  •  ✓ No credit card required  •  ✓ Cancel anytime