Trade Summary

3 days ago, Loscalzo Joseph, serving as Dir at Ionis Pharmaceuticals Inc (IONS), sold 77,289 shares at $75.06 per share, for a total transaction value of $5,801,226.00. Following this transaction, Loscalzo Joseph now holds 36,330 shares of IONS.

This sale represents a 68.00% decrease in Loscalzo Joseph's stake in the company. This is considered a high-conviction trade given the significant change in ownership.

The trade was executed on Monday, May 4, 2026 and publicly disclosed via SEC Form 4 filing on Wednesday, May 6, 2026, 2 days after the trade was made.

Ionis Pharmaceuticals Inc operates in the HEALTHCARE sector, specifically within the BIOTECHNOLOGY industry. Insider selling activity in this sector can provide valuable signals about industry trends and company-specific developments.