Trade Summary

2 days ago, Henderson Michael Thomas, serving as Dir at Spyre Therapeutics, Inc. (SYRE), sold 80,000 shares at $74.40 per share, for a total transaction value of $5,952,050.00. Following this transaction, Henderson Michael Thomas now holds 88,606 shares of SYRE.

This sale represents a 47.00% decrease in Henderson Michael Thomas's stake in the company. This is considered a high-conviction trade given the significant change in ownership.

The trade was executed on Friday, May 8, 2026 and publicly disclosed via SEC Form 4 filing on Friday, May 8, 2026, meaning the disclosure happened on the same day as the trade.

Spyre Therapeutics, Inc. operates in the HEALTHCARE sector, specifically within the BIOTECHNOLOGY industry. Insider selling activity in this sector can provide valuable signals about industry trends and company-specific developments.