Trade Summary

6 days ago, Orbimed Advisors LLC, serving as Dir at Sionna Therapeutics, Inc. (SION), sold 292,952 shares at $45.62 per share, for a total transaction value of $13,364,065.00. Following this transaction, Orbimed Advisors LLC now holds 2,671,822 shares of SION.

This sale represents a 10.00% decrease in Orbimed Advisors LLC's stake in the company. This is considered a high-conviction trade given the significant change in ownership.

The trade was executed on Thursday, May 7, 2026 and publicly disclosed via SEC Form 4 filing on Monday, May 11, 2026, 4 days after the trade was made.

Sionna Therapeutics, Inc. operates in the HEALTHCARE sector, specifically within the BIOTECHNOLOGY industry. Insider selling activity in this sector can provide valuable signals about industry trends and company-specific developments.