Trade Summary

3 days ago, Fairmount Funds Management LLC, serving as Dir at Spyre Therapeutics, Inc. (SYRE), sold 4,684,781 shares at $85.31 per share, for a total transaction value of $399,658,667.11.

This sale represents a 100.00% decrease in Fairmount Funds Management LLC's stake in the company. This is considered a high-conviction trade given the significant change in ownership.

The trade was executed on Tuesday, June 23, 2026 and publicly disclosed via SEC Form 4 filing on Wednesday, June 24, 2026 (accepted Jun 23, 9:56 PM ET), 1 day after the trade was made.

Spyre Therapeutics, Inc. operates in the HEALTHCARE sector, specifically within the BIOTECHNOLOGY industry. Insider selling activity in this sector can provide valuable signals about industry trends and company-specific developments.